Endocrine Neoplasia

Endocrine Neoplasia

The increasing prevalence of endocrine tumors have made endocrine neoplasms an important public health issue. The Endocrine Neoplasia Research Group is committed to providing high-quality research and training in the field of endocrine tumors and diseases. The group comprises surgeons, endocrinologists, radiation oncologist, residents, fellows, health services researchers, epidemiologists, psychologists, and biostatisticians.

The multidisciplinary nature of our group makes it ideal to tackle the pressing issues of endocrine neoplasms and work toward bridging gaps in patient care at the individual and population levels.

Cutting-Edge Research for Cutting-Edge Care

Our research is focused on the different diseases of the thyroid, parathyroid, pancreas, and adrenal glands. Although our primary focus is health services research and health outcomes, we are also interested in examining different issues along the continuum of patient care, including translational research, the psychological and economic impact on patients of endocrine diseases and their subsequent treatment, and patients’ decisions regarding the different diagnostic and treatment strategies available to them.


Endocrine Neoplasia Group's Selected Publications


Probability data could better direct lymph node removal for thyroid cancer

A new study from the DCRI and Duke Cancer Institute strives to establish objective, quantifiable information for patients and doctors regarding the minimum number of lymph nodes that should be analyzed around a tumor for thorough treatment, while reducing risk.

Establishing a minimum number of thyroidectomies a surgeon should perform to optimize patient outcomes

Surgeon-volume outcome relationships have been robustly demonstrated in several surgical procedures, including thyroidectomy. However, a threshold number of cases defining a ‘high-volume’ surgeon had not been established until now.

Minimally Invasive Versus Open Pancreaticoduodenectomy for Cancer

Minimally invasive pancreaticoduodenectomy (Whipple operation) is increasingly becoming popular, especially at specialized centers. This study is the first to examine national patterns of utilization and compare short-term outcomes to those of traditional open surgery.

Project Expertise

Thyroid Cancer

Thyroid cancer is the fastest increasing cancer in the United States. Thyroid cancer is expected to become the third most incident cancer among women, overtaking uterine and colon cancer. This is an important area of research, especially aimed at improving delivery of care, patient outcomes and quality of life. Understanding how to optimize treatment and impacting national guidelines are a few of the areas of interest of our group.

Pancreas and Adrenal Gland

We are interested in discerning optimal management of pancreatic neuroendocrine tumors and tumors of the adrenal gland. Although these clinical entities are rare, their incidence is increasing. Utilizing large administrative databases affords a unique opportunity to investigate and better understand the natural history, national patterns of care, and optimal management of these rare tumors.

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Julie Ann Sosa, MD, MA, FACS

Chief of Endocrine Surgery, Duke University Medical Center
Leader, DCRI Endocrine Neoplasia Disease Program

Dr. Sosa can be contacted at julie.sosa@duke.edu.

Julie Ann Sosa, MD, MA, FACS
Chief of Endocrine Surgery, Duke University Medical Center Leader, DCRI Endocrine Neoplasia Disease Program

"With experts in oncology, radiology, pathology, biostatistics, and other specialties, the Endocrine Neoplasia Research Group at the DCRI provides an impactful, comprehensive approach to the problems caused by endocrine conditions."

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Program Training

The Endocrine Neoplasia Research Group is proud to support and train research fellows, residents and medical students interested in health services research and clinical trials. Our trainees have gone on to spearhead studies that have directly affected the practice of endocrine surgery and the treatment of endocrine cancers. Past trainees have been funded by the DCRI, CTSA, CRTP, NIH, among others.

Past and Current Fellows and Trainees:

  • Mohamed Abdelgadir Adam, MD
  • Kevin Anderson
  • Paolo Goffredo, MD
  • Lauren Gratian, MD
  • Keven Ji
  • Christa Jillard, MD
  • Athos Konstantinidis, MD
  • Lauren Pontius
  • Timothy Robinson, MD, PhD
  • Ewa Ruel, MD
  • Syed Ammer Shah, MD
  • Linda Youngwirth, MD