Implementation Science

Implementation Science

Closing the gap between scientific discovery and patient care must be a top priority.

Our Thinking

As practicing physicians, we never forget to put patients at the center of all we do. Our research is designed to match the demands of a rapidly changing clinical practice environment and establish new treatment standards and guidelines. From bench to bedside, clinical research designed with patient care in mind can help to speed the translation of scientific evidence into practical therapies, changing the healthcare system for the better and improving the lives of patients around the world.

Eric D. Peterson, MD, MPH, FAHA, FACC
Executive Director

"How can we accelerate the adoption of research into practice?"

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Pamela Douglas on PROMISE


Hear Pamela Douglas, MD, discuss the PROMISE trial, a phase IV randomized clinical trial in the diagnostic strategy space comparing the effectiveness of anatomic versus functional testing strategies for the evaluation of chest pain.


Scientific Evidence Underlying Clinical Practice Guidelines


These findings highlight the need to improve the process of writing guidelines and to expand the evidence base from which clinical practice guidelines are derived.

Daniel Benjamin

New NIH-funded center to study inefficiencies in clinical trials


Researchers at the DCRI and Vanderbilt University Medical Center have received a major federal grant to study how multisite clinical trials of new drugs and therapies in children and adults can be conducted more rapidly and efficiently.

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Collaboration: The Baseline Study

“As a clinical research site for the Google Baseline Study, the DCRI will help deliver on the vision for a new kind of medicine—precision medicine—and help to usher in a new model to practice it. Advances in technology now give us the ability to gain insights from huge data sets to accelerate research and see faster progress for patients. This study holds the promise to generate insights about health and transitions between health and disease that will help to transform patient care from reactive to preventative—for multiple conditions, not just a single disease. As a practicing cardiologist and researcher, I am optimistic for the patients I see each day and for patients and generations of families who will benefit from this research.” - L. Kristin Newby, MD, MHS