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PCRC

PCRC logo The Primary Care Research Consortium is a primary care research network for academic, community, Veterans Affairs (VA), and managed-care practices within the Duke University Health System and surrounding communities. PCRC includes 25 practices located across 8 counties in North Carolina. At these practices, there are more than 150 primary-care clinicians providing care for more than 250,000 patients, with access to a total population of 1.2 million.

Mission
The mission of the PCRC is to operate a community-based research network with guidance from an academic medical center, namely the Duke University Health System. Our goals are to

  • Perform trials that will improve healthcare delivery and patient outcomes
  • Provide educational opportunities for clinicians to maintain clinical skills and develop new skills in performing research
  • Offer clinicians support to participate in clinical research through a central administrative office and trained study coordinators
  • Generate research to support the practice of evidence-based medicine.

Site and Study Coordination
The PCRC facilitates site access across multiple therapeutic areas for trials involving ambulatory patients with both chronic and acute disease.
The PCRC model consists of a group of dedicated clinical research nurses trained by the network office PCRC Project Management ensures that study milestones are completed according to timelines. PCRC coordinates contract and financial services for all network practices. Use of this model ensures quality data collection, provides enhanced allocation of site personnel, and protects the sites from fiscal responsibility for a full-time study coordinator position.

The PCRC can act solely as a network for multicenter trials or offer trial coordination of various levels via the DCRI.

Rapid Enrollment

  • 110 patients screened (74 randomized) in 6 weeks for chronic ischemic heart disease study
  • 248 patients randomized in 6 months in a depression study

Contacts
Adult studies: Rowena Dolor, MD, MHS
Pediatric studies: Chip Walter, MD, MPH

If you are interested in joining PCRC and becoming eligible to participate in clinical trials with the DCRI, please take the time to fill out the Investigator Sign-up Sheet.

   

Services to Sites

  • Central study coordination: Mobile study coordinators assist in patient identification, enrollment, data collection, case report form completion, regulatory compliance, and patient follow-up visits. This ensures uniform training of study coordinators to improve the completeness and accuracy of data collection.
  • Central Institutional Review Board (IRB): A single IRB review and approval process ensures quicker and more efficient turnaround for study approvals
  • Central contracts and finances: Contracts and finances are centrally managed and represent all practices within PCRC. The PCRC office maintains the interface with sponsors for administrative issues, project timeline, and milestone definition.

Projects
The PCRC has clinical trials experience in:
  • Acute coronary syndromes
  • Allergic rhinitis
  • Asthma
  • Bronchitis
  • Chronic ischemic heart disease
  • Depression
  • Congestive heart failure
  • Community-acquired pneumonia
  • Hypertension
  • Otitis externa
  • Sinusitis
  • Vaccines

Disease areas of interest in adult or pediatric populations within PCRC practices include:
  • Allergic rhinitis
  • Asthma
  • Attention deficit disorder
  • Bronchitis
  • Chronic obstructive lung disease
  • Congestive heart failure
  • Coronary artery disease
  • Deep venous thrombosis
  • Depression
  • Diabetes mellitus, Type 2
  • Gastroesophageal reflux
  • Headache
  • Hyperlipidemia
  • Hypertension
  • Influenza/viral syndrome
  • Obesity
  • Osteoarthritis
  • Osteoporosis
  • Otitis externa/otitis media
  • Peripheral vascular disease
  • Pharyngitis/tonsillitis
  • Pneumonia
  • Sinusitis
  • Stroke
  • Urinary tract infection
  • Vaccines
  • Women’s health
 

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